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Dividing averages of columns in a heatmap


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I am trying to normalise values in a heatmap by dividingaverages of columns by the average ofcontrol columns. (Please see attached image.)

There are 6 repeats in each row to be averaged. Then averages of A, B and C are each divided by avg(control 1) and D, E and Fare each divided by avg(control 2).

Would I do this with calculated columns, and if so how

Many thanks for your help.

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